Table 4.
Haplotypes demonstrating the most significant association with acute bronchodilator response in CAMP, SEPRACOR and LODO
cohort | rs7793837 | rs4723002 | rs1003929 | rs2284220 | frequency | hap-score | simulated p-value |
---|---|---|---|---|---|---|---|
CAMP | A | A | C | A | 0.6 | 2.29 | 0.026 |
SEPRACOR | A | T | 0.13 | -2.7 | 0.003 | ||
LODO | A | A | 0.74 | 2.28 | 0.019 |
CAMP – Childhood Asthma Management Program, LODO – Low Dose of Theophylline and montelukast trial, Hap-score – the score statistics calculated from Haplo.stats.