Table 3. Estimates of the effect of antidepressant medication treatment on viral suppression, using conventional statistical adjustment vs. inverse probability of treatment and censoring (IPTC) weighting (N=158).
The naïve (unweighted) estimates do not have a causal interpretation and are shown here for comparison purposes only. The estimates from the marginal structural models have the following interpretation: if, contrary to fact, participants are exposed to antidepressant medication at or before the prior visit, then their average odds of achieving viral suppression would be the odds ratio given.
| Odds ratio (95% CI) | P-value | |
|---|---|---|
| Unweighted, crude | 1.55 (1.03–2.31) | 0.034 |
| Unweighted, adjusted | 1.58 (1.07–2.31) | 0.02 |
| Weighted | 2.03 (1.15–3.58) | 0.025 |