Figure 5.

Amounts of IL-6, IFNγ, CCL3, and CXCL2 proteins are greater in the corneas with severe disease when compared with the corneas with mild HSK. Corneas were removed 15 days post ocular infection with HSV-1. Four corneas with mild or severe lesions were pooled per sample and a total of four to five samples were obtained from three experiments. Samples were sonicated in the protease inhibitor cocktail and assayed for the respective cytokines via ELISA. Results are reported as mean ± SEM (n = 4 per group per cytokine). P values were calculated using Student's t-test (**P < 0.01; ***P < 0.001).