Table 3. Odds ratios^a (ORs) and 95% confidence intervals (CIs) for four newly identified SNPs in the 5p12 region.

SNP	High-risk allele frequency (%)		Heterozygous OR (95% CI)	Homozygous OR (95% CI)	Per-allele OR (95% CI)	P for trend
	Cases N = 878	Controls N = 1079				Nomb	Permc
rs6451770_G	46.2	42.4	1.32 (1.07, 1.62)	1.33 (1.02, 1.73)	1.17 (1.03, 1.33)	0.014	0.092
rs12515012_A	38.7	34.8	1.21 (1.00, 1.46)	1.36 (1.03, 1.79)	1.18 (1.03, 1.34)	0.015	0.091
rs13156930_C	61.7	58.1	0.98 (0.76, 1.27)	1.26 (0.97, 1.65)	1.15 (1.01, 1.31)	0.018	0.111
rs16901937_G	35.4	31.2	1.30 (1.07, 1.57)	1.36 (1.01, 1.84)	1.21 (1.05, 1.38)	0.005	0.038
rs16901937_G
ER+/PR+ (N = 190)	38.2		1.30 (0.93, 1.82)	1.77 (1.11, 2.84)	1.32 (1.06, 1.65)	0.009	0.060
ER−/PR− (N = 149)	31.2		1.15 (0.81, 1.64)	0.92 (0.50, 1.69)	1.03 (0.80, 1.32)	0.99	1.00

^aAdjusted for age, geographical region of residence, place of birth, and percent European admixture

^bNominal P value

^c100,000 Permutations