Table 2. Characteristics of study population according to response status.
According to responder status in 5-year follow-up
|
||||||
---|---|---|---|---|---|---|
Baseline (N=906) | Deceased (N=320) | Full responder (N=483) | Short-questionnaire responder (N=25) | Non-responder (N=78) | χ2-test: (P) responder vs Non-respondera | |
Sex | 0.0072 | |||||
Female | 42% | 45% | 38% | 60% | 50% | |
Male | 58% | 55% | 62% | 40% | 50% | |
Age at follow-up (years) | <0.0001 | |||||
−59 | 9% | 7% | 11% | 0% | 12% | |
60–69 | 23% | 18% | 28% | 20% | 15% | |
70–79 | 37% | 33% | 42% | 24% | 24% | |
80+ | 31% | 43% | 20% | 56% | 49% | |
Mean (s.d.) | 73.7 (10.2) years | 76.2 (10.5) years | 71.3 (9.2) years | 79.6 (8.5) years | 76.2 (11.3) years | |
Living with partner at follow-up | NA | NA | 76% | 56% | NA | NA |
School education | 0.1556 | |||||
⩽9 years | 70% | 71% | 69% | 96% | 72% | |
10–11 years | 16% | 16% | 17% | 0% | 14% | |
12+ years | 14% | 14% | 14% | 4% | 14% | |
Location | 0.0057 | |||||
Colon | 63% | 65% | 59% | 84% | 71% | |
Rectum | 37% | 35% | 41% | 16% | 30% | |
Stage | 0.0861 | |||||
I | 24% | 8% | 33% | 36% | 27% | |
II | 32% | 23% | 35% | 52% | 46% | |
III | 30% | 32% | 30% | 8% | 27% | |
IV | 14% | 36% | 3% | 4% | 0% | |
Surgery | 98% | 98% | 98% | 92% | 96% | 0.1043 |
Adjuvant/neoadjuvant therapy | 0.0095 | |||||
No therapy | 54% | 41% | 58% | 80% | 68% | |
Radiotherapy | 2% | 1% | 3% | 4% | 5% | |
Chemotherapy | 30% | 42% | 24% | 16% | 20% | |
Radio- and chemotherapy | 14% | 16% | 15% | 0% | 7% | |
Colorectal cancer recurrence | 0.6694 | |||||
Yes | 19% | 41% | 7% | 8% | 8% | |
No | 80% | 59% | 93% | 92% | 81% | |
Missing | 1% | 0% | 0% | 0% | 12% |
Abbreviation: s.d.=standard deviation. Among the variables included in the analysis, the proportion of missing values was <5% except for burden of treatment (5%), stress (11%), and depression score (6%). In general, older survivors, female survivors, survivors without a partner, and survivors with stage I compared with stage III and IV were more reluctant to provide information on these items. Significant P-values (P<0.05) are highlighted in bold.
Short-questionnaire responders are counted as non-responders.