Table 1. Correlation between TIL density and clinicopathological characteristics in the 105 renal cell carcinomas.
CD45RO
|
CD4
|
CD8
|
|||||||
---|---|---|---|---|---|---|---|---|---|
Lo | Hi | P | Lo | Hi | P | Lo | Hi | P | |
Age at surgery (years) | |||||||||
<60 | 21 | 15 | 0.338 | 18 | 18 | 0.944 | 18 | 18 | 0.944 |
⩾60 | 32 | 37 | 35 | 34 | 35 | 34 | |||
Gender | |||||||||
Female | 14 | 15 | 0.952 | 12 | 17 | 0.249 | 15 | 14 | 0.874 |
Male | 39 | 37 | 41 | 35 | 38 | 38 | |||
T stage | |||||||||
pT1 | 41 | 28 | 0.038 | 40 | 29 | 0.116 | 34 | 35 | 0.234 |
pT2 | 5 | 5 | 5 | 5 | 8 | 2 | |||
pT3 | 6 | 18 | 7 | 17 | 10 | 14 | |||
pT4 | 1 | 1 | 1 | 1 | 1 | 1 | |||
Lymph-node involvement | |||||||||
Absent | 50 | 46 | 0.467 | 49 | 47 | 0.705 | 50 | 46 | 0.282 |
Present | 3 | 6 | 4 | 5 | 3 | 6 | |||
Distant metastases | |||||||||
Absent | 49 | 40 | 0.087 | 49 | 40 | 0.087 | 46 | 43 | 0.559 |
Present | 4 | 12 | 4 | 12 | 7 | 9 | |||
TNM stage | |||||||||
I | 41 | 24 | 0.002 | 40 | 25 | 0.011 | 34 | 31 | 0.379 |
II | 4 | 3 | 4 | 3 | 5 | 2 | |||
III | 2 | 13 | 3 | 12 | 5 | 10 | |||
IV | 6 | 12 | 6 | 12 | 9 | 9 | |||
Nuclear grade | |||||||||
1 | 29 | 15 | 0.011 | 28 | 16 | 0.009 | 26 | 18 | 0.266 |
2 | 20 | 25 | 22 | 23 | 21 | 24 | |||
3+4 | 4 | 12 | 3 | 13 | 6 | 10 |
Abbreviations: TIL=tumour-infiltrating lymphocyte; TNM=tumour-node-metastasis.