Kaplan-Meier curves for survival in (A) three post-temozolomide (TMZ) studies on the basis of the Stupp regimen (OTRT v TTRT, P = .025; OTRT v RTRT, P < .001; TTRT v RTRT, P = .07; all adjusting for age, Karnofsky performance score [KPS], and extent of resection) and (B) pre-TMZ trials v TTRT + RTRT (P = .34, adjusting for age, KPS, and extent of resection).