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. 2011 Nov 4;6(11):e27167. doi: 10.1371/journal.pone.0027167

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Schueler et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Original recordings (A) and statistics of the changes in membrane current (ΔI_m; C) of NBCe1- and NBCe1+CAI- or NBCe1+CAIII-expressing oocytes during application of 5% CO₂/24 mM HCO₃ ⁻-buffered solution in the absence and presence of EZA (10 µM). Original recordings of ΔI_m of CA-expressing control cells without coexpression of NBCe1 (B). By the use of Na⁺-selective microelectrodes the rates of rise of intracellular sodium concentration (ΔNa⁺/t; D, F) were obtained. Original recordings of ΔNa⁺/t of control cells without coexpression of NBCe1 (E). The asterisks above the bars correspond to the control cells without CA expression (−CA) before (−EZA) or during application of EZA (+EZA).