Table 1. Screening for the signature motifs in datasets of gp120 sequences of HIV-1 strains infecting volunteers during AIDSVAX Phase III clinical trials.

AIDSVAX Trial ID:		VAX003			VAX004
Infection Status	Viral sequence	Placebo	Vaccine	p-value	Placebo	Vaccine	p-value
Infected	268-D containing	1	2	0.879	33	105	1.000
Infected	447-52D containing	16	18	0.725	74	168	0.999
Infected	537-10D containing	9	12	0.828	64	142	0.986
Infected	2219 containing	23	12	0.033	85	156	0.588
Infected	2557 containing	21	13	0.099	75	153	0.936
Infected	3074 containing	84	82	0.488	103	181	0.275
Infected	3791 containing	9	9	0.606	1	1	0.584
Infected	Unknown	6	8	n/a	8	24	n/a
Infected	Total	105	106	n/a	127	241	n/a
Not Infected	Total	1143	1155	n/a	1675	3346	n/a