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. 2011 Nov 4;6(11):e27286. doi: 10.1371/journal.pone.0027286

Table 2. PCOS phenotype for PA adult monkeys.

Monkeys Menstrual cycles (mean duration in days) Ovarian morphology Testosterone (ng/ml)
Adult controls
#1 Normal (26) NA 0.12
#2 Normal (28) NA 0.20
#3 Normal (NA) NA 0.21
#4 Normal (27) NA 0.27
#5 Normal (26) NA NA
PA adults
#1 Normal (31) PCO NA
#2 Intermittent/anovulatory (43) PCO 0.20
#3 Intermittent/anovulatory (93) Normal 0.32
#4 Intermittent/anovulatory (70) PCO 0.48
#5 Intermittent/anovulatory (48) Normal 0.40
#6 Intermittent/anovulatory (52) PCO 0.51
#7 Intermittent/anovulatory (120) PCO 0.29
#8 Intermittent/anovulatory (35) PCO 0.37

PA female rhesus monkeys exhibit a variety of phenotypes similar to those found in PCOS women. PA monkey phenotypes were refined from those previously described [61], [62]; intermittent/anovulatory cycles were defined as cycle lengths longer than 34 days because 92% of normal female rhesus monkeys have menstrual cycles between 24–34 days [63]; hyperandrogenism was defined as testosterone ≥0.32 ng/ml, which represents the mean plus one standard deviation in circulating basal testosterone levels of control monkeys [62]. PCO: polycystic ovary morphology, determined from photos taken via laparoscope during transabdominal illumination; PCO was defined as the presence of 10 or more ∼1–3 mm follicles per greatest ovarian diameter [64]. NA: not available or not assessed.