TABLE 2.

RISK RATIOS FOR THE ASSOCIATION BETWEEN PREOPERATIVE BODY MASS INDEX AND GRADE 3 PRIMARY GRAFT DYSFUNCTION

		BMI Category				Continuous BMI
	No.	Normal/Underweight BMI <25 kg/m2	Overweight BMI 25–29.9 kg/m2	Obese BMI ≥ 30 kg/m2	P Trend	Risk Ratio (95% CI) per 5 kg/m2 Increase	P Value
PGD grade 3 within 72 h
Risk	512	17%	37%	42%	<0.001
Model 1	512	1 (Ref)	2 (1.5–2.8)	2.4 (1.9–3.1)	<0.001	1.5 (1.4–1.6)	<0.001
Model 2	512	1 (Ref)	1.9 (1.4–2.6)	2.1 (1.7–2.7)	<0.001	1.4 (1.3–1.5)	<0.001
Model 3	512	1 (Ref)	1.9 (1.4–2.6)	2.1 (1.7–2.6)	<0.001	1.4 (1.3–1.5)	<0.001
PGD grade 3 at 72 h
Risk	512	8%	15%	19%	<0.001
Model 1	512	1 (Ref)	1.9 (1.1–3.4)	2.5 (1.4–4.2)	<0.001	1.5 (1.3–1.8)	<0.001
Model 2	512	1 (Ref)	1.7 (1.1–2.7)	1.9 (1.2–3.1)	0.004	1.4 (1.1–1.7)	0.001
Model 3	512	1 (Ref)	1.8 (1.1–2.9)	1.9 (1.2–2.9)	0.003	1.4 (1.1–1.6)	<0.001

Definition of abbreviations: BMI = body mass index; CI = confidence interval; PGD = primary graft dysfunction.

Effect estimates are risk ratios (95% confidence intervals).

Model 1: Unadjusted model with a random intercept for study center.

Model 2: Adjusted for diagnosis, use of cardiopulmonary bypass, and transplant procedure (bilateral vs. single) with a random intercept for study center.

Model 3: Model 2 + adjustment for systolic pulmonary artery pressure, ischemic time, donor oxygenation, and donor age.