TABLE 3.
COMPARISON OF XPERT SEMIQUANTITATIVE RANGES AND AFB SMEAR RESULTS FOR PELLETED SAMPLES
AFB Smear Grade* |
|||||||
Xpert result (TB Ct range) | Negative | Scanty | 1+ | 2+ | 3+ | Total | |
Very low (28 < Ct ≤ 38) | % | 65.4 | 20.6 | 8.4 | 2.8 | 2.8 | 100 |
n | 70 | 22 | 9 | 3 | 3 | 107 | |
Low (22 < Ct ≤ 28) | % | 25.5 | 19.3 | 37 | 12.8 | 5.4 | 100 |
n | 62 | 47 | 90 | 31 | 13 | 243 | |
Medium (16 < Ct ≤ 22) | % | 4.4 | 1.8 | 21.9 | 22.7 | 49.1 | 100 |
n | 17 | 7 | 84 | 87 | 188 | 383 | |
High (Ct ≤ 16) | % | 1.9 | 0 | 3.2 | 4.4 | 90.5 | 100 |
n | 3 | 0 | 5 | 7 | 143 | 158 |
Definition of abbreviations: AFB = acid-fast bacilli; Ct = cycle-threshold; TB = tuberculosis.
Excludes tests with internal control Ct greater than 34 and tests from site B, which was found to be an outlier in comparisons of average Mycobacterium tuberculosis Cts per smear grade (Figure 6).