Skip to main content
. 2011 Oct 15;184(8):928–938. doi: 10.1164/rccm.201102-0271OC

Figure 4.

Figure 4.

Keap1 deletion in myeloid cells augments antibacterial defenses, whereas Nrf2 deletion disposes to greater bacterial burden. (A) Blood CFUs in mice 24 hours after CLP. No blood CFU was detected in sham surgery group (data not shown); (B) Bacterial burden in peritoneal activity 24 hours after CLP; (C) Inflammatory cells in the peritoneal cavity 24 hours after CLP; (D) Bacterial phagocytic activity of peritoneal macrophages isolated 24 hours after CLP. (E and F) Phagocytosis and killing of bacteria by peritoneal macrophages isolated from healthy mice. Data were analyzed by Student t test; *Significant compared with flox control group; P < 0.05, †Significant compared with LysM-Keap1−/− group; P < 0.01.