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. Author manuscript; available in PMC: 2012 Nov 2.
Published in final edited form as: J Am Chem Soc. 2011 Oct 11;133(43):17126–17129. doi: 10.1021/ja2072324

Figure 1.

Figure 1

Schematic of multi-target immuno-magnetic sorting. (a) Conventional sorting of multiple targets involves lengthy sequential magnetic isolation steps. (b) In contrast, SMD-based sorting technology captures all targets of interest simultaneously, followed by a rapid sorting through release of MB-Target link. (c) Target is captured through immuno-recognition by DNA-encoded antibody and partial hybridization with CP on MB. Selective target release is achieved through sequence-specific EP displacement due to a more favorable hybridization between CP and DP.