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. Author manuscript; available in PMC: 2012 Dec 5.
Published in final edited form as: Virology. 2011 Oct 5;421(1):19–27. doi: 10.1016/j.virol.2011.09.014

Table 1.

Frequency of immortalization of human cervical cells by the complete HPV-16 genome after treatment with erlotinib.

Erlotinib KSFM1 w/o EGF
HCX-1 HCX-2 HCX-3 HCX-1 HCX-2 HCX-3
untreated 6/62 6/6 5/5 6/6 6/6 6/6
0.1 μM 5/6 3/6 5/6 0/5 0/6 0/6
0.3 μM 2/5 0/5 0/6 0/5 0/6 0/6
1.0 μM 0/6 0/6 0/6 0/6 0/5 0/6
1

Immortalization assays were performed in KSFM with 5 ng/ml EGF (3 left columns) or KSFM without EGF (3 right columns). Each column represents an independent experiment using cells from a different sample of cervix.

2

Number of wells with immortal cells/the total number of wells examined.