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. 2011 May 23;30(44):4498–4508. doi: 10.1038/onc.2011.154

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Copyright © 2011 Macmillan Publishers Limited

This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Effect of enforcing IRX1 on tubular formation in vitro. The supernatants from cells with or without IRX1 transfection were collected. After 18 h co-cultivation with HUVECs, tubular formation was evaluated. (a) Poorly formed tubular structure was observed in SCG-7901/IRX1 group, compared with mock or controls. (b) The bar charts represent the counting of tubules number (left, *P<0.001), tubular length (middle, *P=0.022) and intersecting nods (right, *P<0.001) between different groups. The data represent the mean±s.d. of three independent experiments.