Figure 8. Resilience of mitochondrial function in response to DMNQ in differentiated SH-SY5Y cells compared to undifferentiated cells.
DMNQ was added to cells for 4 hr before OCR measurement and continued for 30 min, followed by injection of oligomycin (O), FCCP (F) and antimycin A (A) at indicated times. (A) OCR of Day 0 undifferentiated SH-SY5Y cells treated with 0–20 µM DMNQ. (B) OCR of Day 5 differentiated SH-SY5Y cells treated with 0–20 µM DMNQ. Data = mean ± SEM. OCR was normalized to protein.