Figure 1.
Dendritic Ih loss begins within 1 h after SE and persists for at least 1 month. A, Ih amplitudes at maximal activation obtained from 1 h and 1 d post-SE animals were significantly reduced compared to control. Representative current traces are shown at voltage commands of ∼ −150 mV. Summary data at 1 week are from Jung et al. (2007), and data at 1 month are from Jung et al. (2010). B, Voltage-dependent activation of Ih at 1 h and 1 d post-SE was similar to control. Diagram shows approximate location of dendritic recordings. Ctrl, Control.