Table 5.
LRI, HRI, and TRI values for DGGE fingerprint profiles of total fecal DNA
| Fecal sample | No. of samples | LRI |
HRI |
TRI |
|||||
|---|---|---|---|---|---|---|---|---|---|
| Mean ± SEa | Minimum–maximum | P value | Mean ± SEb | Minimum–maximum | P value | Mean ± SEc | P value | ||
| Cross-sectional | |||||||||
| Patients with CF | 20 | 13.0 ± 1.1 | 3.0–23.0 | 0.63 | 5.9 ± 0.6 | 0.0–11.0 | 0.42 | 19.2 ± 1.4 | 0.65 |
| Siblings | 22 | 13.8 ± 1.2 | 5.0–27.0 | 5.3 ± 0.5 | 5.0–27.0 | 20.6 ± 1.5 | |||
| Longitudinal patient sibling pair 1 | |||||||||
| Patient 1 | 7 | 8.3 ± 1.0 | 6.0–14.0 | 0.02d | 5.4 ± 1.6 | 1.0–14.0 | 0.08d | 13.9 ± 1.9 | 0.28 |
| Sibling 1 | 8 | 15.5 ± 2.8 | 6.0–26.0 | 2.4 ± 0.4 | 1.0–4.0 | 18.1 ± 3.1 | |||
| Longitudinal patient sibling pair 2 | |||||||||
| Patient 2 | 8 | 7.0 ± 1.1 | 4.0–12.0 | 0.22 | 3.5 ± 0.8 | 1.0–8.0 | 0.08 | 11.0 ± 1.5 | 0.16 |
| Sibling 2 | 8 | 10.0 ± 2.1 | 4.0–20.0 | 5.4 ± 0.6 | 4.0–9.0 | 15.6 ± 2.7 | |||
a
Mean number of bands in the low-%GC region of the DGGE fingerprint profile.
b
Mean number of bands in the high-%GC region of the DGGE fingerprint profile.
c
Mean total number of bands in the DGGE fingerprint profile.
d
Significant difference between CF samples and sibling samples (95% CI).