Table 3.

Amino acid similarities to proteins in GenBank and domains in Interpro for ORFs of the putative pAKD15 catabolic pathway^a

ORF no.	% amino acid similarity	Best hit, accession no.	Domain(s)	PFAM/Interpro no.
Orf60	86	Arsenical resistance protein, YP_002943872	NADPH-dependent FMN reductase, arsenate resistance	PF03358, IPR014063
Orf59	40	Protein of unknown function DUF81, YP_002947552	Protein of unknown function DUF81	PF01925
Orf57	31	Methanesulfonate monooxygenase, hydroxylase beta subunit, YP_001020117	Aromatic-ring-hydroxylating dioxygenase beta subunit	PF00866
Orf55	39	Putative dioxygenase subunit, YP_004417630	Aromatic-ring-hydroxylating dioxygenase alpha subunit, aromatic-ring-hydroxylating dioxygenase 2Fe-2S-binding site, Rieske iron-sulfur domain	IPR001663, IPR015881, IPR017941
Orf54	48	Periplasmic isophthalate binding receptor, BAH70270	Bordetella uptake gene	IPR0005064/PF03401
Orf53	43	Transcriptional regulator, IclR family, YP_003607133	Transcriptional regulator IcIR N-terminal, winged HTH transcription repressor DNA-binding, transcriptional regulator IcIR C terminal	PF09339/IPR005471, IPR011991, IPR014757
Orf52	68	Phthalate 4,5-dioxygenase, YP_002947550	NAD-binding domain, FAD-binding domain, 2Fe-2S cluster	PF00111
Orf51	35	Transcriptional regulator, MarR family protein, YP_002298705	Transcriptional regulator HTH MarR type, winged HTH transcription repressor DNA binding	IPR000835, IPR011991
Orf50	45	Extracytoplasmic solute receptor, YP_725900	Bordetella uptake gene	PF03401/IPR005064
Orf49	45	Rieske [2Fe-2S] domain protein, ZP_03542810	Rieske [2Fe-2S] iron-sulfur domain	PF00355/IPR017941
Orf48	44	FAD-dependent oxidoreductase, YP_973874	NAD(P)-binding domain, FAD/NAD(P)-binding domain	SSF51735, SSF51905
Orf47	34	ABC transporter, ZP_07673750	NMT1/THI5-like	PF09084
Orf43	39	GntR family transcriptional regulator, YP_675818	Transcriptional regulator HTH GntR, GntR C terminal, winged HTH transcription repressor DNA binding	IPR000524, IPR011711, IPR011991

^aAbbreviations: FAD, flavin adenine dinucleotide; FMN, flavin mononucleotide; HTH, helix-turn-helix.