Summary of metagenomic screen positives. (A) Overall domain organization of the polypeptide encoded by the longest cDNA of each type. The numbers adjacent to the diagrams indicate amino acid residues. The type 1 cDNA encodes a protein with a single, N-terminal GH5 domain and a C-terminal domain of unknown function. The type 2 cDNA encodes a protein with a single GH10 domain. The type 3 (partial) cDNA encodes a protein with a partial N-terminal GH11 domain and a second C-terminal GH11 domain, whereas the type 4 cDNA encodes a protein with two GH11 domains. (B) Alignment between type 3 and 4 protein sequences, with the GH11 domains indicated by boxes. (C) Domain comparison between type 3 and 4 proteins. Domain I and domain II refer to the first and second GH11 domains, as indicated in panel B. The first number indicates the percent identity, whereas the second number (in parentheses) indicates the percent similarity. “Inter” refers to the interdomain sequence.