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. 2011 Nov;18(11):1925–1935. doi: 10.1128/CVI.05117-11

Fig. 6.

Fig. 6.

Reduction in the levels of pulmonary proinflammatory cytokines in iYp-plus-IL-12–vaccinated BALB/c mice (4/group) 72 h after i.n. challenge with 103 CFU of Y. pestis CO92. ‘×' indicates death of a mouse due to infection. *, P < 0.05; all compared to the PBS or uninfected control groups. Hatched lines represent the limits of cytokine detection by bead-based immunoassay. Error bars represent means ± SD. These results are representative of two independent experiments.