Fig. 6.
Reduction in the levels of pulmonary proinflammatory cytokines in iYp-plus-IL-12–vaccinated BALB/c mice (4/group) 72 h after i.n. challenge with 103 CFU of Y. pestis CO92. ‘×' indicates death of a mouse due to infection. *, P < 0.05; all compared to the PBS or uninfected control groups. Hatched lines represent the limits of cytokine detection by bead-based immunoassay. Error bars represent means ± SD. These results are representative of two independent experiments.