Fig. 3.

Children with TB infection do not have altered production of TGF-β and IL-10. PBMCs from TB (n = 30) and HC (n = 18) children were stimulated with PPD (10 μg/ml), M. tuberculosis CFP (10 μg/ml), or anti-CD3 (5 μg/ml) for 24 h, and levels of the immunoregulatory cytokines TGF-β and IL-10 were measured by ELISA. Results are shown as raw values for nonstimulated and net cytokine production (with medium control values subtracted) for PPD, CFP, and anti-CD3 using bar graphs showing geometric means and 95% confidence intervals. P values were calculated using the Mann-Whitney test.