Fig. 5.

Bacillus Calmette-Guérin vaccination status does not impact the production of type 1, type 2 or type 17 cytokines. PBMC production of IFN-γ, TNF-α, IL-4, and IL-17 following 24-h stimulation with PPD (10 μg/ml) or M. tuberculosis CFP (10 μg/ml) in Bacillus Calmette-Guérin-vaccinated (n = 14) (BCG+) or nonvaccinated (n = 16) (BCG-) TB-infected children is analyzed. Results are shown as raw values for nonstimulated and net cytokine production (with medium control values subtracted) for PPD, CFP, and anti-CD3 using bar graphs showing geometric means and 95% confidence intervals. P values were calculated using the Mann-Whitney test.