Table 2.

Specificities of CL-ELISA with distinct T. cruzi antigens and of conventional serologic methods to heterologous human sera

Disease or infection (n)a	Test resultb	No. of samples with each result with CL-ELISA and:			No. of samples with each result with:
		EpEx	tGPI mucin	TSSA VI	IHA	IIF	ELISA
Leishmaniasis (60)	Positive	36	0	0	35	46	40
	Inconclusive	6	0	1	3	5	0
	Negative	18	60	59	22	9	20
	Specificity	30	100	98.3	36.7	15	33.3
Histoplasmosis (4)	Positive	0	0	0	0	0	0
	Inconclusive	0	0	0	0	0	0
	Negative	4	4	4	4	4	4
	Specificity	100	100	100	100	100	100
Mycobacterium leprae (9)	Positive	0	0	0	0	3	0
	Inconclusive	0	0	0	0	2	0
	Negative	9	9	9	9	4	9
	Specificity	100	100	100	100	44.5	100
Helminth and protozoan infections (28)	Positive	2	0	0	0	0	5
	Inconclusive	2	0	1	0	0	2
	Negative	24	28	27	28	28	21
	Specificity	85.7	100	96.4	100	100	75
Rheumatoid arthritis (53)	Positive	4	0	3	0	4	20
	Inconclusive	1	0	4	0	5	0
	Negative	48	53	46	53	44	33
	Specificity	90.6	100	86.6	100	83.1	62.3
Systemic lupus erythematosus (26)	Positive	4	0	1	2	4	9
	Inconclusive	0	0	0	0	6	0
	Negative	22	26	25	24	16	17
	Specificity	84.6	100	96.2	92.3	61.5	65.4

^an, number of samples from affected individuals.

^bSpecificity is expressed as a percentage.