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. 2011 Nov;10(11):1413–1421. doi: 10.1128/EC.05168-11

Table 2.

Relative fitness coefficients for isolated adaptive mutants compared to the parental isolate used to initiate the culture

Adaptive event Strain No drug
FLUb
Relative fitnessa/ generation P valuea Relative fitnessa/ generation P valuea
8 DP-1-M1 −0.02 ± 0.1 0.74 0.58 ± 0.13 0.01
9 DP-1-M2 0.03 ± 0.01 0.05 0.51 ± 0.1 0.01
10 DP-1-M3 0.07 ± 0.04 0.08 0.71 ± 0.13 0.01
11 DP-1-M4 0.11 ± 0.06 0.07 0.22 ± 0.03 0.00
12 DP-1-M5 −0.1 ± 0.02 0.01 0.68 ± 0.06 0.00
13 DP-1-M6 0.02 ± 0.07 0.50 0.63 ± 0.08 0.00
14 DP-1-M7 0.05 ± 0.02 0.04 0.52 ± 0.05 0.00
15 DP-2-M1 −0.02 ± 0.07 0.63 0.42 ± 0.08 0.00
16 DP-2-M2 0.03 ± 0.01 0.00 0.61 ± 0.01 0.00
17 DP-2-M3 0.11 ± 0.03 0.03 0.62 ± 0.08 0.00
18 DP-2-M4 0.23 ± 0.03 0.01 0.41 ± 0.08 0.01
19 DP-2-M5 0.12 ± 0.02 0.01 0.67 ± 0.08 0.03
20 DP-2-M6 0.15 ± 0.06 0.05 0.61 ± 0.05 0.00
21 DP-2-M7 0.13 ± 0.03 0.01 0.52 ± 0.13 0.02
22 DP-2-M8 0.06 ± 0.04 0.08 0.49 ± 0.01 0.00
23 DP-2-M9 0.19 ± 0.02 0.00 0.47 ± 0.1 0.01
24 DP-2-M10 0.02 ± 0.01 0.03 0.51 ± 0.04 0.00
a

Relative to the parental strain of a different color.

b

FLU, fluconazole.