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. 2011 Nov;85(22):11581–11587. doi: 10.1128/JVI.05662-11

Fig. 2.

Fig. 2.

Expression of influenza virus nucleoprotein (reddish brown) in the bronchus (A) and in lung biopsy specimens (B) by recombinant influenza A virus of rg sw915/H1N2 with the insertion of NA from HK415742/H1N1pdm influenza virus at 48 hpi. (C) Viral replication kinetics in ex vivo cultures of bronchi and lungs infected with 106 TCID50 of HK415742/H1N1pdm, sw915/H1N2, and rg sw915/H1N2 with the insertion of NA from HK415742/H1N1pdm influenza virus by virus titration at 37°C. Colored asterisks indicate statistically significant increases in the viral yield compared to 1 hpi, and black asterisks represent statistically significant differences between HK415742/H1N1pdm and rg sw915/H1N2 with the insertion of NA from HK415742/H1N1pdm. ***, P < 0.0005. The chart showed the means and the standard errors of the means of the virus titer pooled from three independent experiments. Asterisks indicate statistically significant increases in viral yield compare to 1 hpi: *, P < 0.05; **, P < 0.005; and ***, P < 0.0005.