Skip to main content
. 2011 Dec;85(23):12201–12215. doi: 10.1128/JVI.06048-11

Fig. 10.

Fig. 10.

Eosinophilia influx is conserved across group 2b N proteins. Young mice immunized with VRPs expressing the SARS N protein (VRP N); the N protein from another group 2b bat coronavirus, BtCoV.279 (VRP 279 N); or an irrelevant antigen (VRP-HA) were challenged with icGD03, and the lungs were taken 4 days postinfection. (A) Representative images of lung sections (×400) stained with Congo red. The inset shows areas of dense inflammatory infiltrate at higher magnification. (B) Both the SARS N and BtCoV.279 N proteins induce a significant eosinophilic inflammatory influx compared to the irrelevant antigen. ‡, P < 0.0001.