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(a) Two polar layers at the helical core of the ST3:NSP495–146 pentamer. Interactions between Glu120 (red, normal pKa; pink, high pKa) and Gln123 (light blue) are marked as dotted lines. (b) SA11:NSP495–137 tetramer. The calcium ion is shown as a sphere. The ionic interactions between Arg119 (dark blue) and Glu120 (red) and hydrogen bonds between Glu120 (red) and Gln123 (light blue) and the calcium ion are marked as dotted lines.
