Fig. 3.

VACV-infected IFN-γ^−/− mice have higher virus titers in the spleen and liver than WT mice. B6, IFN-γ^−/−, and Prf^−/− mice were infected with 10⁶ PFU VACV i.p., and virus titers in their ovaries, spleens, and livers were determined 7 dpi. Data correspond to individual mice. Horizontal lines and error bars indicate the mean ± SEM for each group and are representative of three independent experiments. *, P = 0.05; **, P = 0.01.