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. 2011 Oct 26;17:2782–2788.

Table 1. Intracellular levels of 8-OHdG and MDA before and after treatment of orbital fibroblasts with 200 μM H2O2.

Oxidative damage Before treatment (mean±SD) After treatment (mean±SD) Induction ratio (%)* (mean±SD) p-value
8-OHdG(ng/mg DNA)
Normal
2.75±0.24
3.52±0.20
128±5
0.005
GO
3.72±0.20
5.12±0.32
138±11
0.005
 
p=0.002
 
p=0.213
 
MDA (nmol/106 cells)
Normal
219.80±35.67
275.33±40.49
126±7
0.027
GO
325.92±10.95
530.95±62.83
163±20
0.007
  p=0.002   p=0.029  

*Induction ratio=after H2O2 treatment value /baseline value (%).