Table 4. GSH/GSSG ratio in orbital fibroblasts before and after treatment with 200 μM H2O2.
Redox status | Basal treatment (mean±SD) | After treatment (mean±SD) | Induction ratio (%)* (mean±SD) | p -value |
---|---|---|---|---|
GSH/GSSG ratio | ||||
Normal |
84.00±15.21 |
65.60±6.68 |
78.94±8.45 |
0.094 |
GO |
43.15±6.10 |
21.58±3.58 |
50.75±10.86 |
0.008 |
p=0.004 | p=0.014 |
*Induction ratio=GSH/GSSG value after H2O2 treatment/baseline value (%).