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FGF10 stimulates the synthesis of MUC1 and MUC4. Epithelial cells from primary culture were stimulated with FGF10 (1, 10, 100, or 200 ng/ml) or bFGF (10 ng/ml) for 24 h (A) or 48 h (B). Cells were scraped and analyzed by western blot with antibodies against MUC1 and MUC4. Representative blots are shown in A and B. Data shown in the chart are mean±SEM from 6 independent experiments. *p<0.05 versus blank (cells treated with 1% FBS).
