Table 2.
Baltic1 441 UC cases/1156 controls |
Danish 560 UC cases/796 controls |
Norwegian1 274 UC cases/282 controls |
European1 3989 co/1822 ca |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | A1 | FCA | FCO | OR | 95% CI | PCCA | FCA | FCO | OR | 95% CI | PCCA | FCA | FCO | OR | 95% CI | PCCA | FCA |
rs7520292 | A | 0.20 | 0.20 | 1.04 | 0.85-1.25 | 0.71 | 0.17 | 0.16 | 1.01 | 0.81-1.24 | 0.94 | 0.16 | 0.16 | 1.00 | 0.73-1.38 | 0.96 | 0.20 |
rs1488266 BTLA | C | 0.06 | 0.06 | 0.95 | 0.69-1.29 | 0.72 | 0.10 | 0.11 | 0.91 | 0.71-1.16 | 0.45 | 0.09 | 0.10 | 0.90 | 0.60-1.36 | 0.64 | 0.10 |
rs3103190 | G | 0.40 | 0.41 | 0.98 | 0.83-1.14 | 0.76 | 0.30 | 0.33 | 0.87 | 0.73-1.02 | 0.09 | 0.31 | 0.31 | 0.99 | 0.77-1.27 | 0.95 | 0.34 |
rs12518307 | A | 0.33 | 0.33 | 1.00 | 0.84-1.17 | 0.99 | 0.27 | 0.23 | 1.19 | 1.00-1.42 | 0.04 | 0.27 | 0.26 | 1.04 | 0.79-1.35 | 0.77 | 0.25 |
rs2395609 TCP11 | G | 0.29 | 0.30 | 0.92 | 0.77-1.09 | 0.35 | 0.34 | 0.33 | 1.04 | 0.88-1.23 | 0.60 | 0.35 | 0.36 | 0.97 | 0.76-1.24 | 0.83 | 0.32 |
rs7809799 SMURF1/KPNA71 | G | 0.07 | 0.05 | 1.42 | 1.03-1.94 | 0.03 | 0.03 | 0.04 | 0.86 | 0.57-1.27 | 0.44 | 0.04 | 0.02 | 1.6 | 0.86-3.23 | 0.11 | 0.05 |
rs6966125 TNP03 | G | 0.21 | 0.20 | 1.01 | 0.83-1.22 | 0.89 | 0.15 | 0.14 | 1.10 | 0.88-1.36 | 0.40 | 0.12 | 0.14 | 0.84 | 0.59-1.19 | 0.33 | 0.16 |
rs638300 | T | 0.15 | 0.14 | 1.09 | 0.88-1.35 | 0.42 | 0.20 | 0.20 | 0.97 | 0.80-1.17 | 0.77 | 0.21 | 0.19 | 1.10 | 0.82-1.48 | 0.49 | 0.21 |
rs6119625 FER1L4 | G | 0.15 | 0.14 | 1.08 | 0.87-1.34 | 0.47 | 0.13 | 0.12 | 1.11 | 0.88-1.39 | 0.37 | 0.13 | 0.10 | 1.28 | 0.89-1.83 | 0.17 | 0.15 |
rs6125345 | C | 0.17 | 0.18 | 0.93 | 0.75-1.13 | 0.45 | 0.19 | 0.16 | 1.20 | 0.88-1.63 | 0.24 | 0.20 | |||||
rs5771069 IL17REL | A | 0.50 | 0.52 | 0.93 | 0.79-1.08 | 0.31 | 0.49 | 0.50 | 0.97 | 0.82-1.12 | 0.67 | 0.43 | 0.53 | 0.69 | 0.54-0.87 | 0.002 | 0.49 |
1Data for the 11 SNPs in the Norwegian panel, for rs5771069 and rs7809799 in the Baltic panel, and the allele frequencies for the combined German, British, Belgian, and Greek panel is from Franke et al [7].
A1: minor allele; F: allele frequency of A1 for cases (FCA) or controls (FCO), respectively; 95%CI: 95% confidence interval; PCCA: P-value (Pearson's χ2 test on allele counts with one degree of freedom); nominal significant P-values are highlighted by bold type