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. 2011 Oct 13;12:139. doi: 10.1186/1471-2350-12-139

Table 3.

Odds ratios (OR) for the combined UC panels and heterogeneity test for the Northern countries (Baltic, Norwegian, and Danish) versus rest of Europe (German, British, Belgian, and Greek).

Baltic, Norwegian, and Danish1
1275 cases and 2234 controls		 German, British, Belgian, and Greek1
1822 cases and 3989 controls		 Northern vs rest of Europe Baltic, Norwegian, Danish, German, British, Belgian, and Greek
3097 cases/6223 controls
SNP A1 PBD ORCMH 95%CI PCMH Power PBD ORCMH 95%CI PCMH PBD ORCMH 95%CI PCMH
rs7520292 A 0.98 1.02 0.89-1.16 0.75 43% 0.13 1.19 1.08-1.32 0.004 0.001 1.13 1.04-1.22 0.003
rs1488266 BTLA C 0.98 0.92 0.77-1.09 0.35 49% 0.50 0.83 0.72-0.95 0.01 0.14 0.87 0.78-0.97 0.01
rs3103190 G 0.54 0.93 0.84-1.03 0.20 30% 0.06 0.86 0.79-0.94 0.001 0.71 0.89 0.84-0.96 0.001
rs12518307 A 0.34 1.07 0.96-1.20 0.18 39% 0.17 0.86 0.78-0.95 0.002 0.007 0.95 0.88-1.02 0.16
rs2395609 TCP11 G 0.59 0.98 0.88-1.09 0.73 39% 0.17 0.84 0.77-0.92 0.0002 0.01 0.90 0.84-0.96 0.002
rs7809799 SMURF1/KPNA71 G 0.09 1.20 0.95-1.52 0.10 94% 0.81 1.43 1.19-1.71 0.0001 0.10 1.34 1.16-1.55 0.00005
rs6966125 TNP03 G 0.45 1.01 0.88-1.16 0.82 54% 0.34 0.83 0.73-0.93 0.001 0.12 0.90 0.83-0.99 0.02
rs638300 T 0.65 1.03 0.91-1.18 0.55 55% 0.10 1.19 1.08-1.31 0.0003 0.18 1.14 1.05-1.23 0.001
rs6119625 FER1L4 G 0.72 1.12 0.97-1.29 0.11 47% 0.90 1.19 1.06-1.33 0.001 0.29 1.17 1.07-1.28 0.0006
rs6125345 C 0.33 1.03 0.90-1.18 0.64 39% 0.45 1.15 1.03-1.27 0.006 0.29 1.11 1.02-1.20 0.01
rs5771069 IL17REL A 0.06 0.89 0.79-0.98 0.02 29% 0.54 0.89 0.82-0.97 0.008 0.86 0.89 0.84-0.95 0.0005

1Data on the 11 SNPs in the Norwegian, German, British, Belgian, and Greek cohort, and on rs5771069 and rs7809799 in the Baltic cohort is derived from the study of Franke et al [7]. In the study by Franke et al [7] the rs5771069 G allele is denoted as the A1 allele, whereas in this study the rs5771069 A allele is denoted as the A1 allele. Combined P-values (PCMH) and combined ORs (ORCMH) of the Cochran-Mantel-Haenszel (CMH) test statistic; Breslow-Day test for odds ratio heterogeneity between countries (PBD); A1: minor allele in healthy controls; F: allele frequency of A1 for cases (FCA) and controls (FCO), respectively; 95%CI: 95% confidence interval; nominal significant P-values are highlighted by bold type;