Table 1. Characteristics of study participants.
| Parameters | Total AMD | |
Case |
Control | ||
|---|---|---|---|---|---|---|
| p-value | nAMD | PCV | RAP | |||
| No. of subjects |
685 |
|
253 |
381 |
51 |
277 |
| Age (mean±SD) |
72.0±8.8 |
0.146 |
73.7±7.5 |
69.9±9.1 |
80.1±6.8 |
72.9±8.7 |
| Male/female |
478/207 |
<0.0001* |
188/65 |
271/110 |
19/32 |
111/166 |
| Hypertension (%) |
39.1 |
0.254 |
38.3 |
39.4 |
41.2 |
43.0 |
| Diabetes mellitus (%) |
10.7 |
<0.0001* |
12.6 |
9.4 |
9.8 |
19.5 |
| Smoking (%) | 34.7 | <0.0001* | 34.8 | 37.3 | 15.7 | 17.7 |
Abbreviations: AMD represents age-related macular degeneration, nAMD represents neovascular age related macular degeneration, PCV represents polypoidal choroidal vasculopathy, RAP represents retinal angiomatous proliferation, N represents number, SD represents standard deviation. Information on hypertension, diabetes mellitus and smoking was obtained from the medical history of each patient. p-values reflect comparisons between case and control groups. p-values were calculated using Fisher's exact test. *p<0.05