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. Author manuscript; available in PMC: 2012 Dec 5.
Published in final edited form as: Eur J Pharmacol. 2011 Sep 24;671(1-3):39–44. doi: 10.1016/j.ejphar.2011.09.162

Fig. 2.

Fig. 2

Effect of sub-chronic administration of vehicle D-142 and imipramine on the duration of immobility in the forced swimming test in rats. One way ANOVA analysis demonstrates significant effect among treatments: F (4,95) = 11.03 (P< 0.0001). Dunnett's analysis showed that the effect of D-142 at three doses (2.5, 5 and 10 mg/kg n immobility was statistically significant different compared to vehicle (P< 0.01). The effect of reference imipramine (15 mg/kg) on immobility was also statistically significantly different (P< 0.01) from vehicle. Asterisks indicate a statistically significant difference toward control group that received saline i.p. **P < 0.01. Each treatment group contained four to seven rats.