TABLE 1.
General characteristics of diabetic rats treated with taurine, arginine and carnitine alone or in combination
| BW, g | HW, mg | LVW, mg | RVW, mg | HW/BW | |
|---|---|---|---|---|---|
| Control | 595±17 | 1466±42 | 961±12 | 271±21 | 2.47±0.04 |
| Diabetes | 383±28* | 1314±87 | 820±63* | 223±14* | 3.45±0.10* |
| Diabetes + taurine | 399±12* | 1257±37* | 828±22* | 208±11* | 3.15±0.04*† |
| Diabetes + arginine | 386±30* | 1351±110 | 842±96* | 250±14 | 3.52±0.20* |
| Diabetes + carnitine | 371±22* | 1170±35* | 748±29* | 214±11* | 3.20±0.11* |
| Diabetes + combination | 399±21* | 1234±46* | 788±36* | 225±14* | 3.12±0.11* |
Data presented as mean ± SE of six to eight animals for each group. Treated diabetic rats were also pretreated with amino acids for three weeks before streptozotocin injection.
*
P<0.05 versus control value;
†
P<0.05 versus nontreated diabetic value. BW Body weight; HW Heart weight; LVW Left ventricular weight; RVW Right ventricular weight