TABLE 2.
Effect of taurine, arginine and carnitine alone or in combination on plasma glucose and lipid profile in diabetic rats
| Glucose, mM | Total cholesterol, mM | Triglycerides, mM | High-density lipoprotein cholesterol, mM | |
|---|---|---|---|---|
| Control | 25.3±1.5 | 2.13±0.12 | 1.60±0.21 | 1.28±0.06 |
| Diabetes | 31.9±1.3* | 2.87±0.24* | 9.18±2.56* | 1.20±0.03 |
| Diabetes + taurine | 34.8±1.2* | 3.34±0.40* | 12.66±2.90* | 1.06±0.07 |
| Diabetes + arginine | 33.3±1.4* | 3.10±0.8* | 12.95±3.10* | 1.29±0.60 |
| Diabetes + carnitine | 36.6±1.9* | 2.95±0.30* | 3.42±0.91*† | 1.72±0.12*† |
| Diabetes + combination | 40.7±1.5* | 2.46±0.39* | 4.11±1.13*† | 1.39±0.16 |
Data presented as mean ± SE of six to eight animals for each group. Treated diabetic rats were also pretreated with amino acids for three weeks before streptozotocin injection.
*
P<0.05 versus control value;
†
P<0.05 versus nontreated diabetes value