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. Author manuscript; available in PMC: 2012 Dec 15.
Published in final edited form as: Neuroscience. 2011 Jun 22;198:232–244. doi: 10.1016/j.neuroscience.2011.06.048

Figure 5.

Figure 5

Examples of electrophysiological recordings from STN cells in a patient with cranial-cervical dystonia (left column) and a patient with akinetic-rigid parkinsonism (PD, right column). A: A 2-s interval of neuronal recordings. B: interspike interval (ISI) histograms, bin size of 1 ms. Inset: expanded timescale demonstrating the absence of ISIs of <3-ms duration, consistent with the neuronal refractory period. C: raster diagrams showing bursting discharge. Bursts as defined by the Poisson “surprise” method (surprise value = 5) are labeled with a black bar above spikes that constitute a burst. Note the higher proportion of bursts per total number of spikes shown in the dystonia neuron (0.40 vs. 0.26 in the PD neuron). Consecutive rows (3 s of data per row) from bottom to top represent continuous 36-s recordings. D: autocorrelograms. The right autocorrelogram shows oscillatory activity of about 11 Hz. The unit on the left was not found to have significant oscillations. Reprinted, with permission, from Schrock et al. (2009).