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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Jun 27;1823(1):15–28. doi: 10.1016/j.bbamcr.2011.06.007

Fig. 9.

Fig. 9

Interaction of ClpX and ClpP. (A) The ClpXP complex is stabilized by peripheral interactions between the IGF loops of ClpX and hydrophobic clefts on ClpP, as well as by axial interactions between the pore-2 loops of ClpX and the N-terminal stem-loop of ClpP. Adapted with permission from ref. [24]. (B) Structure of an acyldepsipeptide (ADEP1; stick representation; 3MT6) bound in one of the ClpP clefts (surface representation) [89]. (C) Model of the ClpX IGF peptide binding in the ClpP cleft in a manner analogous to ADEP1.