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. 2011 Nov;134(3):341–348. doi: 10.1111/j.1365-2567.2011.03494.x

Figure 6.

Figure 6

IRGM1 polymorphisms and Mycobacterium tuberculosis (MTB) -induced cytokine production. Cytokine production capacity of tumour necrosis factor-α (TNF-α) (a, d), interleukin-1β (IL-1β) (b, e) and interferon-γ (IFN-γ) (c, f) by peripheral blood mononuclear cells (PBMCs) obtained from healthy volunteers after stimulation for 24 hr (TNF-α and IL-1β) or 48 hr (IFN-γ) with sonicated MTB stratified for IRGM genotypes. Data are presented as means + SEM. n = 104 (2 AA, 25 GA, 77 GG for rs4958847, and 2 CC, 17 TC, 83 TT for rs13361189).