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. 2011 Jul 4;4(6):814–821. doi: 10.1242/dmm.007328

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© 2011. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.

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Fig. 1. — Growth trajectory of Cdkn1c¹²⁹ mutants. (A) Postnatal weights for wild-type (WT) and Cdkn1c mutant pups on a pure 129 background (WT, 1561±167 mg, n=84; Cdkn1c^−m/+p, 1586±185 mg, n=46; 22 litters; P=0.44). Error bars show standard deviation. (B) Number of wild-type compared with mutant newborns that showed evidence of suckling. (C) Postnatal weights for wild-type and Cdkn1c mutant pups after excluding data from fed animals (WT, 1510±296 mg, n=29 versus Cdkn1c^−m/+p 1567±287 mg, n=42; P=0.132). (D,E) Embryonic weights for wild type and Cdkn1c mutant at (D) E15.5 (WT, 407±84 mg, n=24; Cdkn1c^−m/+p, 468±113 mg, n=21; P=6.27×10⁻⁶) and (E) E18.5 (WT, 1196±129 mg, n=63; Cdkn1c^−m/+p, 1169±169, n=63; P=0.001).