Table 2.
Clinically applied photosensitizers.
| Photosensitizer | Structure | Wavelength (nm) |
Approved | Trials | Cancer types |
|---|---|---|---|---|---|
| Photofrin (HPD) | porphyrin | 630 | World wide | lung, esophagus, bile duct, bladder, brain, ovarian |
|
| ALA | porphyrin precursor |
635 | World wide | skin, bladder, brain, esophagus | |
| ALA esters | porphyrin precursor |
635 | Europe | skin, bladder | |
| Foscan (mTHPC) | Chlorine | 652 | Europe | US | head and neck, lung, brain, skin, bile duct |
| Verteporfin | Chlorine | 690 | World wide (AMD) |
UK | ophthalmic, pancreatic, skin |
| HPPH | chlorin | 665 | US | head and neck, esophagus, lung | |
| Purlytin (SnEt2) | chlorin | 660 | US | skin, breast | |
| Taloporfin, LS11, MACE, Npe6 | chlorin | 660 | US | liver, colon, brain | |
| Fotolon (PVP-Ce6), Radachlorin, Photodithazine |
chlorin | 660 | Belarus, Russia |
nasopharyngeal, sarcoma, brain | |
| Silicon phthalocyanine (PC4) | phthalocyanine | 675 | US | cutaneous T cell lymphoma | |
| Padoporfin (TOOKAD) | bacteriochlorin | 762 | US | prostate | |
| Motexafin lutetium (LuTex) | texaphyrin | 732 | US | breast |