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. Author manuscript; available in PMC: 2011 Nov 7.
Published in final edited form as: Chem Biol Drug Des. 2009 Dec 17;75(2):143–151. doi: 10.1111/j.1747-0285.2009.00921.x

Figure 3.

Figure 3

Enthalpic and entropic contributions to the binding affinity of protease inhibitors. The blue, green, and red bars represent the Gibbs energy of binding (ΔG), the enthalpy change (ΔH), and the entropy change (-TΔS) at 25°C, respectively.