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. Author manuscript; available in PMC: 2011 Nov 7.
Published in final edited form as: Chem Biol Drug Des. 2009 Dec 17;75(2):143–151. doi: 10.1111/j.1747-0285.2009.00921.x

Figure 4.

Figure 4

Correlation between the Gibbs energy of binding (ΔG) and the van der Waals radii of the ortho substituents of the four inhibitors (H: 1.2 Å, F: 1.47 Å, Cl: 1.75 Å, CH3: 2.0 Å; values from Bondi (40, 43)).