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. Author manuscript; available in PMC: 2012 Oct 27.
Published in final edited form as: J Med Chem. 2011 Sep 22;54(20):7150–7164. doi: 10.1021/jm200739e

Figure 3. Colony formation assay.

Figure 3

R2/hPCFT4 cells were inoculated into 60 mm dishes (200 cells per dish), in the presence or absence of a range of concentrations of compound 3, compound 4, LMTX, or PMX. Colonies were enumerated and results are presented as percent of control treated identically but without drugs, as mean values from 3 experiments (plus/minus SEM). IC50s for 3, 4, PMX, and LMTX were 1.4 nM, 27.2 nM, 4.9 nM, and 29.7 nM, respectively.