Table 2.
Selected genes differentially expressed between C57BL/6 (C57) and 2 purported heat-resistant strains, AKR/N (AKR) and/or MRL/MpJ–+/+ (MRL)a
| Affymetrix Fold Change |
||||
|---|---|---|---|---|
| Gene | Gene Symbol | GenBank Accession No. | AKR/C57 | MRL/C57 |
| Apolipoprotein C-II | Apoc2 | NM_009695 | 55.48 | 97.22 |
| Lactoperoxidase | Lpo | NM_080420 | 35.58 | 44.00 |
| Caspase 9 | Casp9 | NM_015733 | 21.77 | 21.81 |
| Cytochrome P450, family 2, subfamily c, polypeptide 55 | Cyp2c55 | NM_028089 | 17.68 | 23.04 |
| Vanin 1 | Vnn1 | NM_011704 | 15.77 | 15.05 |
| Histidine ammonia lyase | Hal | NM_010401 | 12.91 | 11.70 |
| Mitogen-activated protein kinase 14 | Mapk14 | NM_011951 | 12.24 | 11.74 |
| Transcribed locus | — | BM211445 | −312.41 | −77.71 |
| RIKEN cDNA 4930589P08 gene | 4930589P08Rik | AK017048 | −236.58 | −101.88 |
| RIKEN cDNA 1110020P15 gene | 1110020P15Rik | NM_197979 | −37.00 | −56.96 |
| Potassium channel tetramerization domain containing 14 | Kctd14 | NM_001010826 | −20.52 | −24.36 |
| Carboxypeptidase N, polypeptide 1 | Cpn1 | NM_030703 | −17.39 | −21.18 |
| EF hand domain containing 2 | Efhd2 | NM_025994 | −16.97 | −6.93 |
a
All genes must have a raw signal no less than 50 in at least 1 strain and 2-fold or more differences in expression between C57BL/6 and the other 2 strains.