Table 6.
Selected genes differentially regulated by heat stress in C57BL/6 and AKR/Na
| Genes | Gene Symbol | GenBank Accession No. | Affymetrix Fold Change |
|---|---|---|---|
| Differentially up-regulated in C57BL/6 | |||
| Pleckstrin homology-like domain, family A, member 1 | Phlda1 | NM_009344 | 3.8 |
| TYRO protein tyrosine kinase binding protein | Tyrobp | NM_011662 | 3.0 |
| Steroidogenic acute regulatory protein | Star | NM_011485 | 3.0 |
| B-cell translocation gene 2, antiproliferative | Btg2 | NM_007570 | 2.5 |
| Differentially down-regulated in C57BL/6 | |||
| Aminopeptidase-like 1 | Npepl1 | NM_213733 | −3.8 |
| Histone 1, H2ae | Hist1h2ae | NM_175660 | −3.0 |
| Mus musculus resistance to inhibitors of cholinesterase 3 homolog (C. elegans) (Ric3) |
Ric3 | NM_001038624 | −2.9 |
| Hypoxia up-regulated 1 | Hyou1 | NM_021395 | −2.5 |
| Differentially up-regulated in AKR/N | |||
| Heat shock protein 1, beta | Hsp90ab1 | NM_008302 | 4.0 |
| Cysteine and glycine-rich protein 1 | Csrp1 | NM_007791 | 3.4 |
| Phospholipase A2, group VI | Pla2g6 | NM_016915 | 2.7 |
| CCAAT/enhancer binding protein (C/EBP), beta | Cebpb | NM_009883 | 2.5 |
| Differentially down-regulated in AKR/N | |||
| Kalirin, RhoGEF kinase | Kalrn | XM_001001454 | −7.7 |
| Smoothened homolog (Drosophila) | Smo | NM_176996 | −3.1 |
| Sperm acrosome associated 3 | Spaca3 | NM_029367 | −3.0 |
| Helicase with zinc finger domain | Helz | NM_198298 | −3.0 |
a
All genes must have a raw signal no less than 50 in at least 1 of the strains and 2-fold or more regulation in expression between 2 strains.