Table 3. S1P4–R agonist activity of compounds 21a-21g (EC50 nM).
cpd | Ar | EC50 (nm) α |
---|---|---|
21a | NA | |
21b | NA | |
21c | 3800 | |
21d | NA | |
21e | NA | |
21f | NA | |
21g | NA |
Data are reported as mean of n = 3 determinations.
NA = not active at concentrations up to 25 μM.